From SCIENCE: Fear memory in mice is erased by experimental killing of a subpopulation of lateral amygdala neurons

Science 13 March 2009: Vol. 323. no. 5920, pp. 1492 - 1496 DOI: 10.1126/science.1164139

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Reports

Selective Erasure of a Fear Memory

Jin-Hee Han,^1,2,3 Steven A. Kushner,^1,4 Adelaide P. Yiu,^1,2 Hwa-Lin (Liz) Hsiang,^1,2 Thorsten Buch,⁵ Ari Waisman,⁶ Bruno Bontempi,⁷ Rachael L. Neve,⁸ Paul W. Frankland,^1,2,3 Sheena A. Josselyn^1,2,3*

¹ Program in Neurosciences and Mental Health, Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
² Institute of Medical Sciences, University of Toronto, Toronto, ON, M5G 1X8, Canada.
³ Department of Physiology, University of Toronto, Toronto, ON, M5G 1X8, Canada.
⁴ Department of Psychiatry, Erasmus University Medical Center, 3015 CE Rotterdam, Netherlands.
⁵ Department of Pathology, University of Zurich, CH-8057 Zurich, Switzerland.
⁶ I.Medizinische Klinik und Poliklinik, Johannes Gutenberg-Universität Mainz, 55131 Mainz, Germany.
⁷ Centre de Neurosciences Intégratives et Cognitives, CNRS UMR5228 and University of Bordeaux 1, 33405 Talence, France.
⁸ Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

^* To whom correspondence should be addressed. E-mail: sheena.josselyn@sickkids.ca